?:definition
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Molecular assay reagents intended for use in identifying stable and irreversible exchanges (i.e., translocations) between chromosomes 14 band q32 and 18 band q21, usually involving the exchange of the BCL2 gene with the joining region of the immunoglobin heavy chain of chromosome 14. The detection of these translocations may be used a tumor marker. This translocation is present in most patients with follicular lymphomas and in some patients with acute lymphoblastic leukemia.
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