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Molecular assay reagents intended to identify exchanges (i.e., translocations) between chromosome 12, band p12 and chromosome 21 band q22; usually involving genes ETV6 and AML1 (acute myeloid leukemia 1 gene) respectively. This translocation is one of the most frequent translocations found in B cell acute lymphoblastic leukemia of children and is associated with a long disease-free survival. Its detection may be used as a tumor marker.
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