?:definition
|
-
Molecular assay reagents intended for use in identifying exchanges (i.e., translocations) between chromosome 11 band q24 and chromosome 22 band q12, usually involving genes FLI1 and EWSR1, respectively. This translocation is present in sarcomas (e.g., Ewing\'s sarcomas, primitive neuroectodermal tumors); it is also associated with peripheral neuroepithelioma and esthesioneuroblastomas. Its detection may be used as a tumor marker.
|