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  • Molecular assay reagents intended for use in identifying exchanges (i.e., translocations) between chromosome 4 band q21 and chromosome 11 band q23, usually involving genes AF4 and MLL, respectively. This translocation is present in patients with acute lymphoblastic leukemia (ALL) and some patients with acute nonlymphocytic leukemia (ANLL). Its detection may be used as a tumor marker.
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