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  • Serology reagents intended to detect immunoglobulin M (IgM) antibodies to Herpes simplex virus serotypes 1 and 2 (HSV1 and HSV2, respectively), DNA viruses of the family Herpesviridae. HSV1 is transmitted mostly by infected saliva and typically causes nongenital infections; HSV2 is frequently sexually transmitted and is the main etiologic agent of herpes genital infections. Activation of latent herpesvirus is associated with some malignancies. Persistence of the virus for the lifetime of the host is common.
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