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Molecular assay reagents intended to identify vaccinia virus, a virus of the genus Orthopoxvirus that does not occur in nature (being propagated only in the laboratory for use as an active vaccine against smallpox), by detecting the deoxyribonucleic acid (DNA) of the target virus. Vaccinia viruses only cause mild reactions in healthy persons when used as a live-virus inoculator against smallpox; vaccinia smallpox vaccine does not contain and cannot cause smallpox, but approximately one in one million individuals will develop a acute (and even fatal) response to the vaccination.
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