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  • Serology reagents used in tests intended to detect antigens that permit the identification of strains of Streptococcus group A (typically Streptococcus pyogenes), spherical bacteria of the family Streptococcaceae. St. pyogenes is one of the most important bacterial human pathogens, causing a wide range of suppurative diseases (e.g., pharyngitis, otitis media, sinusitis, endocarditis) and nonsuppurative sequelae (e.g., acute rheumatic fever). These antigens are associated with some autoimmune diseases, including rheumatoid arthritis and osteoarthritis.
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