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Immunoassay reagents intended to perform quantitative analyses on a serum, plasma, or whole blood sample to determine brain natriuretic peptide (BNP) or pro-PNB (a PNB precursor). PNB is a protein typically liberated from the myocardium into the blood as a result of regional wall stress in the ventricles. Circulating BNP is associated with adverse ventricular remodeling and as an indicator of poor prognosis. The level of liberated BNP is used mainly in the diagnosis and treatment responsiveness of congestive heart failure.
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