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  • Immunoassay reagents intended to perform qualitative and/or quantitative analyses on a body fluid sample (e.g., serum) to determine myeloperoxidase-antineutrophil cytoplasmic antibodies (MPO-ANCA). Increased circulating levels of MPO-ANCA are associated with chronic lesions and slow deterioration of renal function; they are also found in autoimmune connective tissue diseases. Many patients identified with perinuclear-ANCA using indirect immunofluorescence, a less specific method, have antibodies to MPO-ANCA.
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