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Immunoassay reagents intended to perform qualitative and/or quantitative analyses on a body fluid sample (e.g., serum) to determine circulating antibodies against the enzyme tissue transglutaminase (TG). These antibodies are highly specific and sensitive for an autoimmune disease characterized by a malabsorption syndrome (i.e., celiac disease) affecting both children and adults; this disease is promoted by ingestion of foods containing gluten, such as cereals.
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