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  • Immunoassay reagents intended to perform qualitative and/or quantitative analyses on a body fluid sample (e.g., serum) to determine antibodies to recoverin, a 23 kDalton retinal photoreceptor protein. These antibodies are found in patients with cancer-associated retinopathy (CAR), a rare disease characterized by retinal degeneration and a progressive loss of vision in association with cancer, in the absence of metastatic, infectious, or metabolic complications (i.e., a paraneoplastic neurologic disease). Reagents used to determine recoverin are mainly used in assays intended for early diagnosis of cancer, frequently when only visual symptoms are present.
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