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Immunoassay reagents intended to perform qualitative and/or quantitative analyses on a body fluid sample (e.g., serum) to determine antibodies to one or more of several retinal proteins found in patients with cancer-associated retinopathy (anti-CAR antibodies). This retinopathy is a rare disease characterized by retinal degeneration and a progressive loss of vision in association with cancer in the absence of metastatic, infectious, or metabolic complications (i.e., a paraneoplastic neurological disease). Reagents to determine anti-CAR antibodies are mainly used in assays intended for early diagnosis of cancer.
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