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Immunoassay reagents intended to perform qualitative and/or quantitative analyses on a body fluid sample (e.g., serum) to determine double-stranded DNA (ds-DNA) antibodies. Increased ds-DNA antibody circulating levels are associated with autoimmune connective tissue diseases, such as systemic lupus erythematosus (SLE). These reagents are mostly used in assays intended for detection, diagnosis, and monitoring of SLE patients.
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