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  • Immunoassay reagents intended to perform quantitative analyses on a body fluid sample (e.g., serum, plasma) to measure levels of kanamycin, an aminoglycoside bactericidal agent. Kanamycin is used in the treatment of a wide variety of aerobic gram-negative bacteria and also for some gram-positive bacteria including mycobacteria. Reagents for kanamycin drug level measurement are used to monitor the therapeutic drug level in patients undergoing treatment, either to determine the adequacy of drug treatment or to diagnose a drug overdose or drug-related toxicity. Typical reference levels in blood, in microgram per milliliter, are: peak 20 to 25, predose (trough) 5 to 10, and toxic more than 35.
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