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  • Immunoassay reagents intended to perform qualitative and/or quantitative analyses on a body fluid sample (e.g., serum, urine) to determine riboflavin (vitamin B2), a yellow compound that is an integral part of numerous naturally occurring flavins. Riboflavin and some of its metabolites are excreted into the urine. Decreased levels of vitamin B2 are characterized by the presence of sore throat, hyperemia, stomatitis, and edema of the oral and pharyngeal membranes; deficiency of riboflavin may also cause seborrheic dermatitis and some types of anemias. The functional status of riboflavin is usually determined by measuring the vitamin-dependent activity of the enzyme glutathione reductase (GTR).
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