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  • Immunoassay reagents intended to perform qualitative and/or quantitative analyses on a cervicovaginal secretion sample to determine in a short period of time (typically several minutes) the insulin-like growth factor binding protein 1 (IGFBP-1). The determination of the presence of IGFBP-1 in the vagina (typically using a dipstick) is used to detect premature rupture of fetal membranes in symptomatic or asymptomatic women due to its higher concentration in amniotic fluid than in serum, cervical mucous, urine, and seminal plasma.
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