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  • Immunoassay reagents intended to perform qualitative and/or quantitative analyses on a body fluid sample (typically urine) to determine in a short period of time (typically several minutes) substances present in or secreted by neoplastic urinary bladder tumor cells (i.e., tumor markers). These reagents include antibodies with the capability of binding to antigens associated with urinary bladder tumor, such as complement H-related protein, fragments of cytokeratin 8 and 18, or the nuclear mitotic apparatus protein NMP22. Urinary bladder tumor marker assays are used to obtain information in tumor grade and clinical stage of urothelial carcinomas of the bladder; they are also used to determine tumor reoccurrence.
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