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  • Immunoassay reagents intended to perform qualitative and/or quantitative analyses on a body fluid sample (typically plasma or cerebrospinal fluid) to determine beta-endorphin, an opioid peptide hormone that originates from the same precursor (proopiomelanocortin [POMC]) as adrenocorticotropin (ACTH). Beta-endorphin is a potent analgesic; its action includes sedation, increase of pain threshold, and autonomic regulation of respiration, heart rate, and blood pressure. Levels of beta-endorphin are very low in normal people. Increased levels in plasma are associated with some diseases such as depression; abnormal levels in cerebrospinal fluid are present in depression, schizophrenia, and chronic pain.
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