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  • Immunoassay reagents intended to perform qualitative and/or quantitative analyses on a body fluid sample (typically plasma) to determine the absorption of serotonin (also known as 5-hydroxytryptamine, [5-HT]) by blood platelets (i.e., platelet serotonin uptake). The results are frequently expressed as maximal velocity uptake (Vmax) or as Michalis constant of platelet serotonin uptake (Km); results can also be expressed as platelet uptake index which is the ratio between platelet 5-HT and plasma 5-HT levels. Abnormal values of serotonin uptake are associated with depression, alcoholism, and some neuropsychiatric diseases.
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