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  • Immunoassay reagents intended to perform qualitative and/or quantitative analyses on a body fluid sample (typically plasma or urine) to determine the antidiuretic hormone (ADH), also known as vasopressin or arginine vasopressin. ADH is synthesized in the neurohypophyseal system and stored and secreted by the posterior lobe of the pituitary gland. The major physiological effects of ADH are on the reabsorption of water and concentration of urine by the kidneys and the induction of generalized vasoconstriction with a rise of blood pressure. Measurement of the levels of ADH are useful in the diagnosis of central diabetes insipidous, nephrogenic diabetes insipidous, and syndrome of inappropriate antidiuretic hormone secretion (SIADH). ADH may be determined using either isotopic or nonisotopic immunoassays.
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