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Immunoassay reagents intended to perform qualitative and/or quantitative analyses on a body fluid sample (typically serum) to determine the carboxyterminal telopeptide that originates from one of the two intermolecular sites of the pyridinoline, cross-linking with type I collagen (also known as I-C telopeptide [ICTP]). Increased levels of ICTP are probably not an index of normal bone resorption; they are associated with bone resorption in diseases such as osteoporosis.
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