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  • Immunoassay reagents intended to perform qualitative and/or quantitative analyses on a body fluid sample (typically urine) to determine free or protein-bound pyridinoline (hydroxylysylpyridinoline), a nonreducible cross-link that stabilizes the mature collagen chains within the extracellular matrix; it is found in bone, in hard connective tissues, and in cartilage. Increased levels of pyridinoline in urine occur during bone resorption and/or cartilage degradation (pyridinoline is a marker of bone resorption).
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