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Immunoassay reagents intended to perform qualitative and/or quantitative analyses on a body fluid sample (e.g., serum) to determine peptides produced by some tumors that have the ability to bind to the parathyroid hormone receptors (i.e., parathyroid hormone related peptide [PTHrP]). The presence of PTHrPs is associated with abnormal bone and mineral metabolism; its determination in serum is used to diagnose hypercalcemia produced by a malignant tumor product (frequently from squamous carcinomas) that causes resorption of bone distal to the site of the tumor.
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