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Immunoassay reagents intended to perform qualitative and/or quantitative analyses on a body fluid sample (typically serum) to determine the free component of triiodothyronine (FT3), one of the two main hormones secreted by normal thyroid glands. These assays are very sensitive and permit direct measurement of FT3 (typically only 0.3% of the total circulating T3 in blood) in undiluted serum after ultrafiltration. The determination of FT3, the only fraction of T3 that is metabolically active, is useful for adjusting the total T3 for variations in binding proteins.
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