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Immunoassay reagents intended to perform qualitative and/or quantitative analyses on a body fluid sample (typically serum or feces) to determine the serine proteinase trypsin. There are two types of trypsin: trypsin I, which is cationic and is found in serum either as its precursor trypsinogen or in complexed forms, and trypsin II, which is anionic and is only found in healthy people as its precursor trypsinogen II. Trypsin is used as an indicator of the type and severity of pancreatitis. The level of trypsin in feces and duodenal content is used as an aid in the diagnosis of chronic pancreatitis and cystic fibrosis in neonates and children.
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