?:definition
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Immunoassay reagents intended to perform qualitative and/or quantitative analyses on a body fluid sample (typically serum) to determine the C3 protein and its activation product fragment c (i.e., C3c). C3 is found in both the alternative and the classic pathway of the complement components proteins. Determination of the levels of C3 and/orC3c is used in diagnosis of diseases such as lupus erythematosus, shunt nephritis, and Gram-positive bacteremia; C3-deficient individuals suffer from recurrent bacterial infections and manifest immune complex diseases.
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