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  • Immunohematology reagents including antiglobulin serum (i.e., monospecific antihuman serum) that may react with immunoglobulin G (IgG) specific alloantibodies bound to the red blood cells being tested. Monospecific antiglobulin serum is mostly obtained through hybridoma technology. Tests performed with monospecific reagents avoid in vitro binding with antibodies that are not usually of clinical significance (e.g., cold reactive antibodies).
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