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  • Immunohematology reagents used in ABO blood grouping that consist of known anti-A and/or anti-B sera. Cells from a person of an unknown group are reacted with known sera. Cells agglutinated only with anti-A serum are group A, those agglutinating only with anti-B serum are group B, and those agglutinating with both antiserum are AB. Cells which fail to agglutinate with either antiserum are group O. Monoclonal antibodies of human or mouse origin are frequently used in ABO grouping. These sera may be used either in manual or automated tests.
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