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  • Hematology reagents used to determine the time required for thrombin to convert fibrinogen to an insoluble fibrin clot when fibrin formation is triggered by the addition of reptilase (a snake venom enzyme) to the specimen, therefore bypassing prior steps in the coagulation cascade. This test does not measure deficiencies in the intrinsic or extrinsic pathways of coagulation; the test is only intended to measure levels of fibrinogen. The reptilase time is not affected by heparin and only slightly affected by fibrinogen degradation products.
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