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  • Immunoassay reagents to determine a group of glycoproteins normally found in serum that are synthesized in and secreted by plasma cells (immunoglobulins [Ig]); these reagents include antigens with the capability of binding to the immunoglobulins. Immunoglobulins are classified in five general classes designated as IgG, IgM, IgA, IgD, and IgE; typically all immunoglobulins are present in serum (IgE that is found normally only in trace amounts). Increased levels of Ig in serum are associated with immune responses and infections. Low levels of Ig in serum are typically found in immunodeficiency diseases.
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