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Molecular assay reagents intended to identify mutations in the human epidermal growth factor receptor 2 (HER2/NEU) gene (also known as ERBB2), located at chromosome 17q11.2-q12, which encodes for growth factor receptors. Mutations at this locus have been identified in patients with breast cancer; they are also associated with other cancer tumors, including primary lung tumors and non-small cell lung cancer (adenocarcinomas) and gastric, ovarian, brain, and testicular tumors.
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