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  • Molecular assay reagents intended to identify mutations in the v-myc myelocytomatosis viral oncogene homologue (MYC, also known as c-Myc) gene, located at chromosome 8q24, which encodes for a multifunctional, nuclear phosphoprotein that is involved in cell cycle progression, apoptosis, and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations at this locus have been identified in patients with hematopoietic tumors, leukemias, and lymphomas, including Burkitt\'s lymphoma.
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