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  • Serology reagents intended to detect immunoglobulin G (IgG) antibodies to hepatitis B virus core antigens. These antibodies typically appear in serum at the onset of disease, usually two or three months after exposure. Hepatitis B viruses are DNA viruses of the genus Hepadnavirus, family Hepadnaviridae. Hepatitis B virus may cause hepatitis, a disease characterized by jaundice and the increase of some enzymes in serum (e.g., aspartate aminotransferase); these viruses may be transmitted percutaneously (e.g., via body piercing, tattooing), parenterally, from mother to child at birth, or by intimate (e.g., sexual) contact.
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