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Immunohematology reagents, including antiglobulin serum (e.g., polyspecific antihuman serum), that may react with the alloantibodies bound to the red cells under test. Antiglobulin serum is obtained either by the injection of an animal with human globulin or through hybridoma technology. Antiglobulin reagents used for detection and/or identification of antibodies in blood may be specific to detect gamma globulin (monospecific), or for detection of both gamma globulin antibodies and complement components (polyspecific).
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