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Hematology reagents used for qualitative and/or quantitative determination in plasma of coagulation inhibitors of the lupus type, consisting of immunoglobulins of either the IgG or IgM class. These inhibitors inhibit various coagulation reactions involved in the intrinsic and common paths; they are not only present in systemic lupus erythematosus but in other, varied groups of disorders, including rheumatoid arthritis, valvular heart disease, and benign prostatic hyperplasia.
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