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  • Molecular assay reagents intended for use in identifying stable and irreversible rearrangements in the sequence (i.e., inversion) of chromosome 16 [inv(16)(p13q22)]. This inversion is often present in patients with a subgroup of acute myeloid leukemias that have a favorable prognosis. In these cases, the inversion is usually the result of the fusion of the CBF and MYH11 genes.
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