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  • Serology reagents intended to detect antibodies to exotoxins produced by several antigenically distinct types of Streptococcus group A (typically Streptococcus pyogenes), spherical bacteria of the family Streptococcaceae. S. pyogenes is one of the most important bacterial human pathogens, causing a wide range of suppurative diseases (e.g., pharyngitis, otitis media, sinusitis, endocarditis) and nonsuppurative sequelae (e.g., acute rheumatic fever). These antibodies are associated with some rheumatic autoimmune diseases.
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