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  • Immunoassay reagents intended to perform qualitative and/or quantitative analyses on a body fluid sample (e.g., serum, plasma, urine) to determine salycilate, a product of the hydrolysis of aspirin (acetylsalicylic acid). Salicylate is the pharmacological agent of the action of aspirin (e.g., analgesic, antipyretic, anti-inflammatory), with the exception of platelet inhibition. Reagents for determination of salicylate concentration are used to assess the severity of overdose intoxication. The therapeutic level of salicylate in serum is lower than 60 mg/L for analgesic and/or antipyretic use and 150 to 300 mg/L for anti-inflammatory purposes; toxic effects are frequent when the level exceeds 300 mg/L.
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