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  • Immunoassay reagents intended to perform quantitative analyses on a body fluid sample (e.g., serum, plasma) to measure levels of tobramycin, an aminoglycoside bactericidal agent. Tobramycin is used in the treatment of a wide range of aerobic gram-negative bacteria and also for some gram-positive bacteria. Reagents for tobramycin level measurement are used to monitor the drug levels in patients undergoing treatment, either to determine the adequacy of drug treatment or to diagnose a drug overdose or drug-related toxicity. Typical reference levels in blood, in micrograms per milliliter, are peak 5 to 8, predose (trough) 1 to 2, and toxic more than 10.
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