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  • Immunoassay reagents intended to perform qualitative and/or quantitative analyses on a body fluid sample (e.g., serum, urine) to determine vitamin B12, the generic descriptor of a group of biologically active substances known as cobalamins. Vitamin B12 is frequently identified with cobalamins that have similar biological activity as cyanocobalamin. Decreased levels of vitamin B12 are associated with pernicious anemia. Deficiency of vitamin B12 may cause neurologic disorders such as pain and loss of sensation of the limbs, weakness, paralysis, and even dementia that may occur without apparent hematologic changes.
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