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  • Immunoassay reagents intended to perform qualitative and/or quantitative analyses of a sample of body fluids (e.g., serum, urine) to determine the level of aldosterone, the major mineralocorticoid hormone secreted by the adrenal cortex; its secretion is stimulated by angiotensin II. Very high levels of aldosterone (i.e., aldosteronism) are associated with plasma volume expansion, hypertension, and edema; they may occur due to overproduction of aldosterone (e.g., adrenal adenoma) or secondary due to extra adrenal diseases such as nephrotic syndrome or congestive heart failure.
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