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Immunoassay reagents intended to perform qualitative and/or quantitative analyses of a sample of body fluids (e.g., serum, urine) to determine the beta subunit (free and/or core fragment) of the glycoprotein hormone human chorionic gonadotropin (beta-HCG). Quantitative tests for beta-HCG in serum are used to establish estimates of fetal age, and determine abnormalities in pregnancy (e.g., ectopic pregnancy, uncertain outcome of abortion, molar pregnancy) and are combined with other markers to improve the detection of fetal abnormalities such as Down\'s syndrome.
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