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Immunoassay reagents intended to perform qualitative and/or quantitative analyses of a sample of body fluids (typically serum) to determine estradiol (E2), the most potent natural estrogen, derived mainly from the ovaries. Typically both free and bound fractions are measured. Estradiol is a sex steroid vital for human reproduction. Its level varies during the menstrual cycle. Estradiol determination is used to evaluate the ovarian function. Levels of estradiol may be high in gynecomastia and cirrhosis.
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