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  • Immunoassay reagents intended to perform qualitative and/or quantitative analyses or a sample or body fluids (typically serum) to determine the total thyroid binding proteins (TBP), a group of proteins (albumin, prealbumin, and globulin) that binds both thyroxin (T4) and triiodothyronine (T3); individual TBPs are typically determined using electrophoresis. The level of TBPs is mostly determined in patients with normal thyroid hormones (i.e., euthyroid patients) to differentiate abnormalities in the concentration of normal T4 binding proteins (either congenital or drug induced) from abnormal binding proteins that have altered affinity for T4 (e.g., congenital variants of albumin).
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