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  • Immunoassay reagents intended to perform qualitative and/or quantitative analyses of a sample of body fluids (typically serum) to determine the free component of thyroxin (FT4), one of the two main hormones secreted by normal thyroid glands. These assays are very sensitive and permit direct measurement of FT4 (typically only 0.03% of the total circulating T4 in blood) in undiluted serum after ultra filtration. The determination of FT4, the only fraction of T4 that is metabolically active, is more indicative of the clinical state of the thyroid than the total level of T4; thus, FT4 determinations are useful to establish both hyperthyroidism and hypothyroidism.
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