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  • Clinical chemistry reagents intended to perform qualitative and/or quantitative chemical analysis of body fluids (typically urine) to measure the level of porphobilinogen (PBG), a porphyrin precursor. Measurement of the level of PBG in urine is the primary assay performed when an acute neurological porphyria is suspected. The measurement of the levels of both PBG and delta-aminolevulinic acid (ALA), another porphyrin precursor, is used to differentiate among several types of porphyrias and other conditions that are clinically similar to porphyrias (e.g., lead poisoning, characterized by high levels of ALA but normal PBG).
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