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  • Clinical chemistry reagents intended to perform qualitative and/or quantitative chemical analysis of a serum sample to determine the total level of protein. Total protein level in serum is usually high (i.e., hyperproteinemia) in dehydrated patients, with the concentrations of all the individual proteins increased to the same degree; in patients with low water intake or severe water loss caused by vomiting or diarrhea; and in patients with certain diseases (e.g., diabetic acidosis). The level is low (i.e., hypoproteinemia) in cases of increased plasma water volume as the result of intoxication, salt retention diseases, or a long period in a recumbent position. Hyperproteinemia may also occur as a result of malignant diseases. Low levels of albumin are a frequent cause of hypoproteinemia.
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