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  • Clinical chemistry reagents intended to perform qualitative and/or quantitative chemical analyses of body fluids (typically serum) to determine the level of the enzyme lactate dehydrogenase; this enzyme is typically measured indirectly (i.e., the enzyme \'activity\'). Methods used for lactate dehydrogenase determination may use either the forward reaction (i.e., the oxidation of L-lactate to pyruvate) or the reverse reaction (i.e., the reduction of pyruvate to L-lactate). Lactate dehydrogenase activity is typically increased in myocardial infarction, in liver diseases (especially toxic hepatitis with jaundice), and in some malignant diseases.
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