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Immunoassay reagents intended to perform qualitative and/or quantitative analyses of body fluids to determine transferrin (also known as siderophilin), a beta-globulin protein that is the main plasma protein that binds and transports iron. Transferrin (TRF) is also capable of binding other metals, such as copper, calcium, zinc, and cobalt. The level and degree of iron saturation of TRF is used as a differential diagnosis in anemia. High transferrin levels are associated with pregnancy or estrogen administration; low levels of TRF are found in the inherited disease atransferinemia, as well as in malnutrition, inflammation, and malignancies.
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