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Immunoassay reagents intended to perform qualitative and/or quantitative analyses on a body fluid sample to determine hemopexin, a plasma glycoprotein that irreversibly binds to free heme (a product of the breakdown of hemoglobin into heme and globin); the combined product is removed by the liver. Decreased levels of hemopexin are found in plasma after hemolysis; as hemopexin is not a protein that reflects acute inflammation (i.e., it is not an acute-phase reactant). Its periodic determination is a better indicator of hemolysis when acute inflammation and hemolysis are concurrent.
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